I’m not quite sure what you are asking?

H, James. Congrats on taking the jump to creative writing. I hope you find it as rewarding as I have. There are different kinds of character weaknesses; some are physical, like the diabetes and broken leg example that you mentioned. For those, I think it would be best to think in terms of goals, since weaknesses always get in the way of a character getting what he most wants and needs. So think of what your character wants, and ask yourself: What about his body would make it difficult for him to achieve that goal? Maybe it’s obesity, a speech impediment, being too short or too tall, having diabetes or chronic sinusitis or bad breath…the possibilities really are endless.

But the biggest weaknesses that block our characters are often their flaws. Angela and I have written a thesaurus on this, cataloguing the different kinds of flaws that might plague a character, what might have caused those flaws to form, how they might manifest, etc. To see them, just browse our list of entries for the Character Trait Thesaurus. If that looks like information that might come in handy, we expanded the list when we published this thesaurus in book format. It’s separated into two separate volumes, one for positive attributes and one for character flaws. You can find information about both books on our Bookstore page. I hope this helps. Best of luck with your writing!